Elizabeth Scarr Selected Research

Muscarinic M1 Receptor

9/2021	Changes in cortical gene expression in the muscarinic M1 receptor knockout mouse: potential relevance to schizophrenia, Alzheimer's disease and cognition.
1/2020	Muscarinic M1 and M4 receptors: Hypothesis driven drug development for schizophrenia.
1/2020	Higher levels of α7 nicotinic receptors, but not choline acetyltransferase, in the dorsolateral prefrontal cortex from a sub-group of patients with schizophrenia.
1/2018	Low levels of muscarinic M1 receptor-positive neurons in cortical layers III and V in Brodmann areas 9 and 17 from individuals with schizophrenia.
1/2018	Low levels of muscarinic M1 receptor-positive neurons in cortical layers III and V in Brodmann areas 9 and 17 from individuals with schizophrenia.
11/2016	The distribution of muscarinic M1 receptors in the human hippocampus.
5/2016	Changes in BQCA Allosteric Modulation of [(3)H]NMS Binding to Human Cortex within Schizophrenia and by Divalent Cations.
1/2016	COMT genotype is associated with differential expression of muscarinic M1 receptors in human cortex.
11/2015	The effect of a muscarinic receptor 1 gene variant on grey matter volume in schizophrenia.
6/2012	Muscarinic M1 receptor sequence: preliminary studies on its effects on cognition and expression.

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Elizabeth Scarr Research Topics

Disease

60	Schizophrenia (Dementia Praecox) 09/2021 - 09/2003
16	Bipolar Disorder (Manic Depressive Psychosis) 12/2020 - 04/2005
12	Mood Disorders (Mood Disorder) 01/2020 - 01/2007
10	Major Depressive Disorder (Major Depressive Disorders) 01/2020 - 02/2012
10	Mental Disorders (Mental Disorder) 11/2016 - 02/2008
3	Inflammation (Inflammations) 02/2018 - 01/2013
3	Psychotic Disorders (Schizoaffective Disorder) 02/2009 - 09/2008
2	Alzheimer Disease (Alzheimer's Disease) 09/2021 - 01/2017
2	Nervous System Diseases (Neurological Disorders) 05/2012 - 08/2009
1	Parkinson Disease (Parkinson's Disease) 01/2017
1	Mania (Manias) 05/2014
1	Huntington Disease (Huntington's Disease) 01/2014

Drug/Important Bio-Agent (IBA)

20	Cholinergic Agents (Cholinergics)IBA 01/2020 - 02/2006
18	Proteins (Proteins, Gene)FDA Link 09/2021 - 03/2006
16	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 01/2020 - 02/2006
13	Messenger RNA (mRNA)IBA 01/2021 - 08/2005
12	Muscarinic M1 ReceptorIBA 09/2021 - 02/2006
12	Antipsychotic Agents (Antipsychotics)IBA 01/2021 - 09/2003
8	PirenzepineIBA 01/2017 - 05/2007
4	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 11/2016 - 12/2004
4	Biomarkers (Surrogate Marker)IBA 03/2016 - 03/2009
4	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 03/2016 - 01/2007
4	Glutamic Acid (Glutamate)FDA Link 01/2013 - 08/2005
4	ApolipoproteinsIBA 01/2010 - 09/2003
3	Pharmaceutical PreparationsIBA 01/2020 - 04/2012
3	Neurotransmitter Agents (Neurotransmitter)IBA 02/2018 - 04/2006
3	Antidepressive Agents (Antidepressants)IBA 04/2016 - 06/2014
3	Imipramine (Janimine)FDA LinkGeneric 04/2016 - 06/2014
3	Fluoxetine (Prozac)FDA LinkGeneric 04/2016 - 06/2014
3	Dizocilpine Maleate (Dizocilpine)IBA 03/2016 - 08/2005
3	KetanserinIBA 06/2014 - 12/2004
3	Serotonin (5 Hydroxytryptamine)IBA 01/2013 - 12/2004
3	N-Methylaspartate (NMDA)IBA 02/2012 - 08/2005
3	Apolipoproteins E (ApoE)IBA 01/2010 - 09/2003
3	EnzymesIBA 08/2009 - 12/2004
3	GTP-Binding Proteins (G-Protein)IBA 08/2009 - 08/2006
3	Guanosine 5'-O-(3-Thiotriphosphate)IBA 08/2009 - 02/2006
2	Biological ProductsIBA 12/2020 - 03/2009
2	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2020 - 05/2012
2	AFDX 384IBA 04/2016 - 12/2015
2	oxotremorine MIBA 04/2016 - 08/2009
2	ProteomeIBA 03/2016 - 03/2009
2	MicroRNAs (MicroRNA)IBA 03/2016 - 03/2009
2	Dopamine (Intropin)FDA LinkGeneric 01/2016 - 01/2013
2	LigandsIBA 08/2012 - 09/2008
2	DNA (Deoxyribonucleic Acid)IBA 06/2012 - 09/2003
2	Kainic Acid (Kainate)IBA 02/2012 - 08/2005
2	Kainic Acid Receptors (Kainate Receptor)IBA 02/2012 - 08/2005
2	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 02/2012 - 08/2005
2	Ionotropic Glutamate ReceptorsIBA 02/2012 - 08/2005
2	Neuregulin-1 (Neuregulin 1)IBA 12/2010 - 02/2008
2	gamma-Aminobutyric Acid (GABA)IBA 09/2010 - 08/2005
2	MuscimolIBA 09/2010 - 08/2005
2	GABA-A Receptors (GABA(A) Receptor)IBA 09/2010 - 08/2005
2	BenzodiazepinesIBA 09/2010 - 08/2005
2	Clozapine (Clozaril)FDA LinkGeneric 02/2009 - 09/2008
2	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 12/2008 - 03/2008
2	Glycogen Synthase Kinase 3 betaIBA 03/2008 - 12/2004
2	Haloperidol (Haldol)FDA LinkGeneric 12/2006 - 03/2006
2	Sumatriptan (Imigran)FDA LinkGeneric 12/2006 - 12/2004
1	Amyloid (Amyloid Fibrils)IBA 09/2021
1	Carrier Proteins (Binding Protein)IBA 01/2020
1	xanomelineIBA 01/2020
1	Prion ProteinsIBA 01/2020
1	Ceruloplasmin (Ferroxidase)IBA 01/2020
1	Choline O-Acetyltransferase (Choline Acetyltransferase)IBA 01/2020
1	IronIBA 01/2020
1	RNA (Ribonucleic Acid)IBA 12/2019
1	RutheniumIBA 01/2019
1	CadmiumIBA 01/2019
1	Trace Elements (Biometals)IBA 01/2019
1	StrontiumIBA 01/2019
1	Amino Acids FDA Link 02/2018
1	Therapeutic UsesIBA 01/2018
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2018
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2018
1	Divalent CationsIBA 05/2016
1	Muscarinic M2 ReceptorIBA 04/2016
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 03/2016
1	Ketamine FDA LinkGeneric 03/2016
1	LY 341495IBA 01/2016
1	ZincIBA 01/2016
1	CatecholaminesIBA 01/2016
1	zinc-binding protein (zinc binding protein)IBA 01/2016
1	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 01/2016
1	Disks Large Homolog 4 ProteinIBA 12/2015
1	Glial Fibrillary Acidic ProteinIBA 12/2015
1	Scopolamine (Hyoscine)FDA Link 01/2015
1	Cholinergic ReceptorsIBA 09/2014
1	Medroxyprogesterone Acetate (Depo-Provera)FDA LinkGeneric 05/2014
1	Progestins (Progestagens)IBA 05/2014
1	Tamoxifen FDA LinkGeneric 05/2014
1	Hormones (Hormone)IBA 05/2014
1	MedroxyprogesteroneIBA 05/2014
1	Selective Estrogen Receptor Modulators (SERM)IBA 05/2014
1	Muscarinic M4 ReceptorIBA 05/2013

Therapy/Procedure

3	Aftercare (After-Treatment) 01/2018 - 02/2008
2	Therapeutics 05/2014 - 12/2008
1	Precision Medicine 03/2016
1	Drug Therapy (Chemotherapy) 05/2013